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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGR All Species: 4.55
Human Site: S450 Identified Species: 12.5
UniProt: P06401 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06401 NP_000917.3 933 98981 S450 P A S A S V S S A S S S G S T
Chimpanzee Pan troglodytes A7X8B3 933 98902 S450 P A S A S V S S A S S S G S T
Rhesus Macaque Macaca mulatta Q6QT55 895 96519 L421 A S S S W H T L F T A E E G Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q00175 923 99056 P445 P S S A A V S P A S S S G S A
Rat Rattus norvegicus Q63449 923 99389 P444 A P S A A V S P V S S S G S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510439 499 56093 A95 G T G Q G E G A R K R E D W N
Chicken Gallus gallus P07812 786 85725 A382 Q A L G F P A A V L K E G L P
Frog Xenopus laevis NP_001079100 732 82004 K328 T F Q P T S M K E T Y L S E I
Zebra Danio Brachydanio rerio XP_001923769 617 69335 P213 W M S A A D S P F W Y Q S A N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 32.6 N.A. N.A. 80.4 81.2 N.A. 45.7 56.2 47 36.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 46.8 N.A. N.A. 85.2 85.8 N.A. 50.2 65.9 58.5 48.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 N.A. N.A. 73.3 60 N.A. 0 13.3 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 40 N.A. N.A. 86.6 66.6 N.A. 6.6 26.6 13.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 34 0 56 34 0 12 23 34 0 12 0 0 12 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 0 0 0 0 12 0 0 % D
% Glu: 0 0 0 0 0 12 0 0 12 0 0 34 12 12 0 % E
% Phe: 0 12 0 0 12 0 0 0 23 0 0 0 0 0 0 % F
% Gly: 12 0 12 12 12 0 12 0 0 0 0 0 56 12 0 % G
% His: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 0 0 0 0 12 0 12 12 0 0 0 0 % K
% Leu: 0 0 12 0 0 0 0 12 0 12 0 12 0 12 0 % L
% Met: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % N
% Pro: 34 12 0 12 0 12 0 34 0 0 0 0 0 0 12 % P
% Gln: 12 0 12 12 0 0 0 0 0 0 0 12 0 0 12 % Q
% Arg: 0 0 0 0 0 0 0 0 12 0 12 0 0 0 0 % R
% Ser: 0 23 67 12 23 12 56 23 0 45 45 45 23 45 0 % S
% Thr: 12 12 0 0 12 0 12 0 0 23 0 0 0 0 23 % T
% Val: 0 0 0 0 0 45 0 0 23 0 0 0 0 0 0 % V
% Trp: 12 0 0 0 12 0 0 0 0 12 0 0 0 12 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _